New Delhi, Dec 19: India is well on its way to having the second-largest metro network in the world with 993 km of Metro rail already operational in 23 cities across the country and about 997 km under construction in 28 cities, Minister for Housing & Urban Affairs Manohar Lal Khattar has said.

The Union Minister made an elaborated presentation on Urban Transport to the consultative committee members of Parliament attached to MoHUA, according to an official statement on Thursday.

He emphasised that Urban Mobility is an important aspect to tackle the rising urban population and the government is working relentlessly to strengthen the Urban Transport Network across the country.

The participants were briefed about Metro Rail Policy 2017 and Metro Networks across the cities including Delhi, Jaipur, Patna and Lucknow.

The members were also briefed about the ongoing projects of RRTS (Regional Rapid Transport System) high speed train network, including its funding pattern.

The briefing to members also covered initiatives taken to promote indigenisation of technologies under Make in India and promote Aatmanirbhar Bharat.

The briefing also mentioned PM-eBus Sewa, a scheme for augmenting city bus operations by deploying 10,000 e-buses on the Public Private Partnership (PPP) model.

Salient features of this scheme include deployment of 10,000 e- buses on PPP model, bus operations support for 10 years, support for development and the upgradation of bus depots and support for behind-the-meter power infrastructure.

The service aims to cover cities with 3 to 40 lakh population.

The briefing also covered ‘One Nation One Card’, an indigenously developed National Common Mobility Card (NCMC), launched by Prime Minister Narendra Modi in March 2019 to enable seamless travel through Metro, Rail, Bus and other Public Transport Operators.

During the meeting, the Members of Parliament raised issues pertaining to urban mobility which included matters related to last mile connectivity, enhancement of amenities, metro connectivity in their respective states, scaling up of metro operations in the country, ease of travel and passenger comfort.

The MPs who attended the meeting include Rajiv Pratap Rudy, Dinesh Sharma, Ajay Maken, Kamaljeet Sherawat, P.N. Vasava, Prof V.E. Gaikwad, Kavita Patidar, B.M. Sutariya , V.E. Vaithilingam , G. Lakshminarayana, Ramvir Singh Bidhuri and Y. Chandolia.

The Minister asked the officials that suggestions from members received should be reviewed and information sought by them should be provided.

New Delhi, Dec 19: The first blood-stage malaria vaccine RH5.1/Matrix-M has the potential to be a component within a developing malaria vaccine strategy, said a report on Thursday.

The report by GlobalData, a data and analytics company, showed that there are 11 other malaria vaccines currently in Phase II development.

As per a recent study by researchers in Burkina Faso and the UK, RH5.1/Matrix-M is safe, effective, and highly immunogenic.

The double-blind, randomised, controlled, phase 2b trial, analysed 361 children between the ages of 5 and 17 months showed that RH5.1/Matrix-M is 55 per cent effective against clinical malaria when administered in a delayed third-dose regimen at 0, 1, and 5 months.

Further, the vaccine demonstrated over 80 per cent efficacy against high levels of malaria parasites, which indicates the vaccine would be effective at preventing severe disease. RH5.1/Matrix-M was found to be generally safe and well-tolerated, with no serious adverse events being reported, revealed the findings published in The Lancet Infectious Diseases.

“RH5.1/Matrix-M has the potential to be the first blood-stage malaria vaccine brought to market. This could be a much-needed addition to the currently available malaria vaccines and provide an important second line of defense for those most at risk of contracting malaria,” said Stephanie Kurdach, Infectious Disease Analyst at GlobalData.

Malaria is a mosquito-borne disease, caused by parasitic Plasmodium protozoans, spread primarily through the bite of an infected female Anopheles mosquito. Typically, the symptoms can range from fever, chills, and headache to confusion, seizures, and difficulty breathing.

Kurdach noted that although there is progress and some nations have been certified as malaria-free, the burden of malaria remains high, particularly within the World Health Organization’s (WHO) African Region.

There are currently only two malaria vaccines, that are WHO prequalified and recommended for use in children: GSK’s Mosquirix and Serum Institute of India’s R21/Matrix-M.

These vaccines work to intercept malaria infection by targeting the early sporozoite stage of the parasite.

However, as immunity wanes with time, sporozoites can infect the liver and lead to blood-stage clinical malaria infection.

The development of a blood-stage malaria vaccine would replace these vaccines as well provide a second line of defense.

“There are 11 other malaria vaccines currently in Phase II development, including pre-erythrocytic vaccines and blood-stage vaccines from manufacturers such as BioNTech, GSK, the National Institute of Allergy and Infectious Diseases (NIAID), and Vac4All SAS,” Kurdach said.

“No new malaria vaccines are in Phase III development or pre-registration at this time,” she added.

New Delhi, Dec 19: Global automaker Range Rover on Thursday announced the start of sales for the 2025 ‘Made in India’ Range Rover Sport in the country.

The ‘2025 Range Rover Sport’ – the first made-in-India vehicle exclusively for the country– is now available in smooth and powerful 3.0l Petrol Dynamic HSE and 3.0l Diesel Dynamic HSE variants, the Tata Motors Group company said in a statement.

The pricing of the New Range Rover Sport now starts at Rs 1.45 crore, ex-showroom, and is available in five colour options – Fuji White, Santorini Black, Giola Green, Varesine Blue and Charente Grey.

Available in 3.0l Petrol Dynamic HSE and 3.0l Diesel Dynamic HSE variants, the Range Rover Sport is built on the state-of-the-art MLA-Flex platform, offering next-level capability, performance and handling, as well as greater efficiency.

“With the introduction of new features such as perforated semi-aniline leather seats, massage front seats and head-up display, our discerning clients will get an elevated experience of comfort and technology in Range Rover Sport,” said Rajan Amba, Managing Director, JLR India.

The 13.1‑inch curved touchscreen for Pivi Pro infotainment is complemented by intuitive 13.7‑inch Interactive Driver Display, with ‘Software Over The Air’ as well as ‘Head-Up Display.’

The 2025 Range Rover Sport offers semi-aniline leather seats, renowned for their exceptional quality and tactility.

In September, Tata Motors held the groundbreaking ceremony of its new Rs 9,000 crore facility in Tamil Nadu that will manufacture and export next-gen vehicles for Tata Motors and Jaguar Land Rover (JLR).

Situated at Panapakkam in Ranipet district, the plant will cater to both domestic and international markets, while creating over 5,000 jobs. Tata Motors Group intends to invest Rs 9,000 crore in this greenfield manufacturing facility, which has been designed for an annual production capacity of over 250,000 vehicles.

Production will begin in a phased manner and progressively increase to reach this capacity over the next 5-7 years.

In May this year, Tata Motors-owned JLR said it plans to start assembling the flagship Range Rover model, along with Range Rover Sport, in India for the first time, significantly bringing down the prices.

The company’s Pune plant currently assembles the Range Rover Velar, Range Rover Evoque, Jaguar F-PACE, and Discovery Sport models.