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WHO strongly advises against antibody treatments for Covid patients

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The World Health Organisation (WHO) has strongly advised against antibody treatments for Covid-19 patients, saying antibody drugs sotrovimab and casirivimab-imdevimab are not working on new variants like Omicron.

These drugs work by binding to the SARS-CoV-2 spike protein, neutralising the virus’s ability to infect cells.

A WHO Guideline Development Group of international experts in the British Medical Journal (BMJ) BMJ said that almost all well-informed patients would not choose to receive sotrovimab or casirivimab-imdevimab.

The strong recommendation replaces previous conditional recommendations for their use and is based on emerging evidence from laboratory studies that these drugs are not likely to work against currently circulating variants, such as Omicron.

In the same update, the WHO made a conditional recommendation for the use of the antiviral drug remdesivir in patients with severe Covid-19, and a conditional recommendation against its use in patients with critical Covid-19.

These recommendations are based on results from five randomised trials involving 7,643 patients, showing 13 fewer deaths per 1,000 patients with severe Covid-19 taking remdesivir, but 34 more deaths per 1,000 patients with critical Covid-19 taking the drug.

“These new trial data provided sufficiently trustworthy evidence to demonstrate benefits in patients with severe Covid-19, but not critical Covid-19. The panel considered the benefits of remdesivir to be modest and of moderate certainty for key outcomes such as mortality and mechanical ventilation, resulting in a conditional recommendation,” said the update.

The WHO also advised that three drugs used to treat arthritis – the IL-6 receptor blockers tocilizumab or sarilumab and the JAK inhibitor baricitinib – may now be combined, in addition to corticosteroids, in patients with severe or critical Covid-19.

This advice is based on new high-certainty trial evidence confirming a survival benefit for baricitinib with little or no serious adverse events when given in combination with corticosteroids and IL-6 receptor blockers.

However, the panel acknowledged some cost and resource implications associated with these drugs, which, they say, could exacerbate health inequities.

Previously, the WHO has made a strong recommendation for use of nirmatrelvir and ritonavir, and a conditional recommendation for molnupiravir for high-risk patients with non-severe covid-19. WHO advises against the use of ivermectin and hydroxychloroquine in patients with covid-19 regardless of disease severity.

Maharashtra

Government Must Clarify Its Stand on VHP’s Ban on Muslims at Navratri Garba-Dandiya Events: SP MLA Raees Shaikh

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Mumbai: The Vishwa Hindu Parishad has issued illegal regulations to ban Garba Dandiya games for Muslim youth during Navratri starting from October 11. The state government should clarify its stand in this regard and show that no one is above the law, demanded Samajwadi Party’s Bhiwandi East MLA Raees Sheikh on Sunday. In this regard, MLA Raees Sheikh said that festivals create harmony in the society and there is a tradition of participating in festivals of other religions in India. People of other religions participate happily in Eid and Ramzan. However, Muslims are being deliberately targeted by the Vishwa Hindu Parishad and Bajrang Dal. Recently, in New York, RSS chief Mohan Bhagwat had made a statement that ‘one who does not say ‘Muslims are not Hindus’. The Vishwa Hindu Parishad must not have taken notice of Bhagwat’s statement while issuing a fatwa to ban Garba Dandiya for Muslims. It is the policy of RSS and BJP to present one idea and actually do the opposite, this is cultural policing by Vishwa Hindu Parishad and Bajrang Dal. Vishwa Hindu Parishad’s fatwa to ban Muslims is against the Indian Constitution. The state government should take serious note of this order. Because the possibility of creating a law and order problem due to such an extremist stance cannot be ruled out. Festivals are the culture of Indians and a celebration of sharing communal feelings. However, recently extremist organizations like Bajrang Dal and Vishwa Hindu Parishad are trying to incite religious sentiments and incite riots during festivals. MLA Raees Sheikh has demanded that the state government take notice of this and put a ban on such acts.

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Maharashtra

Mumbai: Two Key Accused Arrested for Online Fraud in the Name of a Profitable Business

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Mumbai: Police has claimed to have arrested 02 main accused from Jaipur, Rajasthan, who were involved in online fraud by creating a fake Facebook page in the name of Mumbai Wizard Traders 7 and making more profits through it. The complainant woman, who lives under the limits of Oshiwara Police Station, found a Facebook page while surfing on Facebook through her mobile on July 12, 2026. The said page was created in the name of wizard traders 7 and its URL was https://facebook-com/1221162594405776. She had made a post on the said page. In it, the accused had said that by depositing Rs. 99, she would get Rs. 9999. It was written like this. When the complainant clicked on the aforementioned Facebook page, he received a message from this WhatsApp number 8426965923. An unknown person from the aforementioned number informed the complainant about this scheme. When the complainant told him about taking the Rs 99 scheme, he sent Rs 99 through Google Pay on the QR code sent by him and sent him a screenshot of it. After this, the accused contacted the complainant from different mobile numbers till 03:30 pm on July 13th and on different pretexts, forced the complainant to transfer a total of 22 transactions from his account to different accounts, thereby defrauding him of a total of Rs. 73,521. Therefore, a case was registered under Sections 318(4), 319(2) BNS and Sections 66(c), 66(d) IT Act 2000 on the complaint filed by the complainant at Oshiwara Police Station. According to the statement given by the complainant in the said case, the first accused used the Facebook page wizard traders7 used in the case. After taking the information of this Facebook account, the two main accused who committed the said crime were identified and the following accused were followed by the cyber team of Oshiwara Police Station, Mumbai from Jaipur district, Doosa district of Rajasthan state for the last 04 days. They were changing their address from time to time. The accused were arrested with the help of local police from the local police station, Shiv Daspora, South Jaipur, Rajasthan. The accused were produced before the Andheri Court and sent to police custody till September 7. The items used in the crime were also recovered from the possession of the accused. These include 02 iPhone company mobiles worth Rs. 70,000, 01 Oppo company mobile worth Rs. 10,000, a total of 11 old used SIM cards of different mobile companies, 01 NSDL Bank debit card number, 01 Paytm company QR scanner with its UPI ID paytm.s2gotdq@pty. The accused have been identified as Deepak Sitaram Meena, aged 21, unemployed, Talab village, Taluka Lalsot, District Doosa, State of Rajasthan, Harkesh Gopal Meena, aged 30, unemployed, Rajasthan Jankap Colony, Taluka Kotpotli, District Jaipur, State of Rajasthan. After arresting both of them, the police have started further action and in this case, the police have also started checking the bank accounts of the accused. The said action was carried out under the guidance of the staff of Mumbai Oshiwara Police Station and DCP Parshottam Karad.

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Maharashtra

An example of Hindu-Muslim unity at the Dahi Handi celebration in Mahim, Mumbai.

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Mumbai: Setting an example of Hindu-Muslim unity in Mumbai, the Govinda Pathaks have offered the first salute at the entrance gate of the Astana of Maham Hazrat Makhdoom Faqih Ali Mahim. The trustee of the dargah, Sohail Khandwani, said that this is the specialty of India that here everyone respects each other’s religion and the Maham Dargah is the cradle of Hindu-Muslim unity and unity. Everyone attends here without any discrimination, religion or nationality. This is the reason why the Govinda Pathaks offer salute here every year in the traditional way. This tradition has been established for centuries because India is a country of Sufi saints. In the backdrop of Gokul Ashtami Dahi Handi, the police have issued an alert at the Mumbai police station. The police used drones to monitor the Govinda Pathaks. The height of the dahi handi was also fixed. In addition, children were banned from participating in high dahi handi. The festival of Dahi Handi was celebrated with enthusiasm in Mumbai city and its suburbs. In view of this, the traffic police had also blocked the highways so that action could be taken against the violation of traffic rules. Under this, the traffic police has also taken action against the violation of traffic rules. Mumbai Police Commissioner Devin Bharti had claimed that strict security arrangements were made for Dahi Handi in Mumbai city. Accordingly, DCP Raj Tilak Roshan said that the police are fully prepared for Dahi Handi and the situation is also being monitored. Apart from this, surveillance is also being carried out using drones. DCP Raj Tilak Roshan has also appealed for compliance with the law on Dahi Handi. According to the information received from various government and BMC hospitals about the injured Govindas till noon, more than 25 Govinda Pathaks have been injured while the Dahi Handi festival is still going on. In such a situation, BMC hospitals are constantly on alert mode, along with the police, there is also an alert. No untoward incident of any kind took place during Dahi Handi in Mumbai, however, there have been incidents of Govinda Pathaks getting injured and many have been discharged after treatment. Govinda Pathaks gave the first salute from the Astana of Mumbai’s Maham Hazrat Makhdoom Faqih Ali Mahayami and presented proof of Hindu-Muslim unity and solidarity. This Govinda Mandal raises the slogan of Baba Makhdoom and Maa Sahib ki Jai every year by giving the salute at the Astana of Makhdoom in the same style. This is a slap in the face of the haters. It promotes solidarity and unity. The police had made strict security arrangements at Dahi Handi, due to which no untoward incident of any kind took place in Mumbai.

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