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Newly discovered bat coronavirus can spread to humans like Covid-19: Experts

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New Delhi, Feb 22: The newly discovered bat coronavirus — HKU5-CoV-2 — can spread to humans like Covid-19, said experts on Saturday, raising fresh health concerns.

HKU5-CoV-2 was identified by a team of Chinese virologists led by Shi Zhengli, a renowned scientist at the Wuhan Institute of Virology in China. She is also known as “Batwoman” for her extensive research on coronaviruses, particularly the SARS-CoV-2 virus — responsible for the deadly pandemic that claimed millions of lives.

The discovery raises concerns about the possibility of another zoonotic spillover. HKU5-CoV-2 belongs to the merbecovirus subgenus, which includes the MERS-CoV virus that caused the Middle East Respiratory Syndrome outbreak.

Zhengli’s team had, a few years ago, discovered the HKU lineage of coronaviruses in bats from Hong Kong, but it lacked the ability to infect human cells.

On the other hand, “HKU5-CoV-2 is able to bind to human ACE-2 receptors and infect lab cell models of human lungs and intestines. It is also capable of binding to ACE-2 receptors in other mammals, which means it could theoretically spread from animals to man and vice versa,” said Rajeev Jayadevan, Chairman of the Kerala State IMA Research Cell, told media.

The expert noted that Wuhan researchers have not provided a comparison between HKU5-CoV-2 and SARS-CoV-2 in their ability to infect human cells.

However, Gautam Menon, Dean, Research, at Ashoka University said that the HKU5-CoV-2 does not have pandemic potential. “From what we know as of now, this is unlikely to be significant. HKU5-CoV-2 has interesting similarities to Covid-19 and to some other coronaviruses known to infect humans, but that isn’t enough to infer that it will spread between humans in a way that could cause a pandemic,” Menon told IANS.

He further noted that wide exposure to SARS-CoV-2 virus may provide immunity against the new bat coronavirus. “The fact that most people on the planet have been exposed to Covid-19 by now should also protect against viruses, such as HKU5-CoV-2,” Menon said, while stressing the need to continue research in this area to prepare for any contingency.

Jayadevan that while research on viruses that naturally live in bats is important, studying these viruses in laboratories also carries inherent risks.

“If proper biosecurity measures are not followed, there is a potential for accidental spillover to humans. To mitigate these risks, many labs studying high-risk pathogens operate under stringent Biosafety Level 4 (BSL-4) protocols,” he said.

He emphasised the need to decrease interactions between bats and humans. “Viruses are known to recombine with each other, creating new versions with greater abilities. This study is a reminder that viruses living naturally in other animals remain a threat for future pandemics in man, and reducing bat-human interactions is one way to lower the risk of spillovers,” Jayadevan said.

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India takes lead in extreme heat risk management under PM Modi’s leadership

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New Delhi, June 7: India has taken a proactive and forward-thinking approach to extreme heat risk management under the leadership of Prime Minister Narendra Modi, said Dr PK Mishra, Principal Secretary to the Prime Minister.

Delivering the keynote address during the Special Session on Extreme Heat Risk Governance in Geneva, he underlined that rising temperatures posing a systemic risk to public health, economic stability, and ecological resilience.

“India welcomes the United Nations Office for Disaster Risk Reduction’s (UNDRR) initiative to advance the Common Framework for Extreme Heat Risk Governance as a platform for shared learning, guidance, and collaboration,” he told the gathering, according to a Prime Minister’s Office (PMO) statement on Saturday.

Dr Mishra pointed out that India has moved beyond disaster response toward integrated preparedness and mitigation strategies. Since 2016, the National Disaster Management Authority (NDMA) has developed comprehensive national guidelines on heatwave management, revised in 2019, which laid the foundation for decentralised Heat Action Plans (HAPs).

He acknowledged the pioneering ‘Ahmedabad Heat Action Plan’, which demonstrated how early warnings, inter-agency coordination, and community outreach can save lives.

“Over 250 cities and districts across 23 heat-prone states have operational Heat Action Plans, supported by NDMA’s advisory, technical, and institutional mechanisms”, said the Principal Secretary, underscoring that strengthened surveillance, hospital readiness, and awareness campaigns have significantly reduced heatwave-related mortality.

India’s approach is whole-of-government and whole-of-society, engaging ministries from health, agriculture, urban development, labour, power, water, education, and infrastructure.

“Extreme heat deeply impacts communities, and India has actively incorporated traditional wisdom and local experiences into its response”, said Dr Mishra.

He noted that schools have become catalysts for behavioural change, educating children about climate resilience. He also emphasised that hospitals and primary health centres must be strengthened to ensure swift and effective emergency responses.

Outlining India’s transition from a preparedness-only approach to long-term heatwave mitigation, including cool roof technologies, passive cooling centres, urban greening, and the revival of traditional water bodies, Mishra affirmed that India is integrating Urban Heat Island (UHI) assessments into city planning.

He called for a global focus on developing a localised heat-humidity index based on real-time data to enhance early warning systems, advancing building technologies and passive cooling innovations that are affordable and culturally appropriate and addressing equity concerns, as extreme heat disproportionately affects women, outdoor workers, the elderly, and children.

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Study shows how Covid virus shields itself during replication

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New Delhi, June 6: US researchers have identified a mechanism that SARS-CoV-2 — the virus that causes Covid-19 — uses to protect itself inside the body as it works to replicate and infect more cells.

Without this protective mechanism, viral infection is dramatically reduced, said the team from the Texas Biomedical Research Institute and the University of Chicago.

The finding, published in the journal Nature Communications, not only provides a potential target for new Covid therapies but also offers insights that could inform future vaccine and antiviral development.

The study builds on earlier work from Texas Biomed that identified ORF3a, a type of viral protein most important for the virus’s pathogenicity, or ability to cause disease.

Specifically, the team found that SARS-CoV-2 ORF3a appears to play a vital role in protecting structural proteins, most notably the spike protein that facilitates spread into other cells, as they are assembled on the surface of viral particles.

It does this by driving the formation of a dense group of proteins that surround the spike protein and provide protection while in transit, much like security detail protecting a person or an armoured vehicle carrying cash to the bank, the researcher said.

Jueqi Chen, Assistant Professor at the University of Chicago, termed these protective complexes “3a dense bodies” or 3DBs for short.

It appears that 3DBs help prevent the spike protein from being cut into smaller components.

When ORF3a is missing, these 3DBs fail to form, and the spike protein often arrives damaged, severely impairing the nascent virus’s ability to infect new cells, the expert said.

“ORF3a could therefore be a good target for drugs to block the virus,” said Luis Martinez-Sobrido, Professor at Texas Biomed.

“This discovery could also be instrumental for vaccine development, as we illustrated previously,” Martinez-Sobrido added.

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World Environment Day: Ministers call to stop plastic pollution, embrace sustainability

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New Delhi, June 5: Union Ministers on World Environment Day on Thursday urged citizens to put an end to plastic pollution and embrace sustainability while also planting more trees for a greener and cleaner future.

World Environment Day is observed every year on June 5. The theme this year, ‘Beat Plastic Pollution’ aims to end plastic pollution.

“As we mark #EnvironmentDay today, let’s reaffirm our commitment to protecting our planet and ensuring sustainability for all living beings. Always remember nature protects when protected,” said Bhupender Yadav, Union Minister for Environment, Forest and Climate Change (MoEFCC), in a post on social media platform X.

“On World Environment Day, let us renew our commitment to protect the planet by planting more trees, reducing pollution, conserving resources, and embracing sustainability. Together, our small steps can create a greener, healthier, and more hopeful future for all,” added Pralhad Joshi, Union Minister of Consumer Affairs.

Globally, an estimated 11 million tonnes of plastic waste leak into aquatic ecosystems each year, while microplastics accumulate in the soil from sewage and landfills, due to the use of plastics in agricultural products.

Jitendra Singh, Union Minister of State (Independent Charge) for Science and Technology stated that India “reiterates its strong commitment to beat plastic pollution through proactive policies, sustainable practices and mass awareness. Together, let’s restore ecosystems, conserve biodiversity, and build a greener, cleaner future”.

“Let us take a pledge on this Environment Day – stop plastic pollution, live in harmony with nature, and create a greener, cleaner, and safer earth for future generations,” added Kirti Vardhan Singh, Union Minister of State for MoEFCC.

Besides choking the planet, plastic pollution permeates even our bodies in the form of microplastics and poses several health risks.

“Plastic pollution is choking our planet – harming ecosystems, well-being, and the climate. Plastic waste clogs rivers, pollutes the ocean, and endangers wildlife,” said UN Secretary-General António Guterres.

“And as it breaks down into smaller and smaller parts, it infiltrates every corner of Earth: from the top of Mount Everest to the depths of the ocean; from human brains; to human breastmilk,” he added, calling for a movement for urgent change.

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