Maharashtra
Mumbai startup develops India’s first universal gene test for infectious disease

Mumbai-based health-tech startup HaystackAnalytics has developed the first of its kind universal infectious diseases (ID) gene test to identify existing and emerging infections, the company said on Monday.
The company is supported by the Department of Science and Technology, as well as several private healthcare players.
To identify infections, the company deploys Next-Generation Sequencing (NGS) technology and Artificial Intelligence (AI), and also provides information on drug resistance to support and identify correct treatment options for patients.
The new Universal Infectious Diseases test will be rolled out with their current partners in a phased manner over the next three months, the company said in a statement.
It will initially be targeted at identifying and treating sepsis in Intensive Care Unit (ICU) patients, but gradually be made available to anyone suffering from a fever of unknown origin, by eradicating the need to conduct multiple tests.
The test comes at an opportune time, as Covid-19 pandemic highlights the need for better diagnostic technologies, appropriate antibiotic use, and the renewed importance of infection prevention strategies.
“The test enables rapid (within hours) and comprehensive (covering nearly all known bacterial and fungal pathogens) screening in a near to point of care deployment. Leveraging the power of next generation sequencing and AI, the team of scientists and engineers at Haystack has been able to eliminate the need for a redundant and expensive battery of tests, with a single test,” Dr. Anirvan Chatterjee, Co Founder and CEO of HaystackAnalytics, said.
“Our single point focus is to prevent each and every death caused due to treatable infections. Genomics has the potential to reduce trial and error in disease management and bring equality of access to high quality healthcare,” he added.
In the past, HaystackAnalytics had partnered with various diagnostic centers and over 20 hospitals including AIIMS, to introduce their sequencing-based clinical products for Tuberculosis and Covid in the past.
It is while working on two of the most debilitating infectious diseases — Tuberculosis and Covid — the company said it recognised the true burden of inaccurate diagnosis of infections in India and the world.
While the novel coronavirus infected and killed millions of people across the globe, there are various other infectious diseases that continue to plague India.
In particular, India accounts for the largest number of sepsis cases (11.3 million) and sepsis-related deaths (2.9 million) in the world, as per a global study published in the Lancet in 2020.
Despite having a wide range of antibiotics and antifungal medicines, sepsis is a life-threatening organ failure. It occurs when the body ends up injuring its own tissues and organs, in response to an infection, leading to shock, disability, multi-organ failure, and even death if left untreated in the early stages.
“A large proportion of these deaths can be avoided by early and accurate identification of the pathogen causing the infection. Haystack’s UID test has been developed to solve this exact problem,” Chatterjee said.
Maharashtra
Maharashtra: Shiv Sena (UBT) Warns Of Protests Over Potholes And Unsafe Bridges In Palghar

Palghar: Shiv Sena (UBT) has taken a strong stance against the many hazardous potholes, unsafe bridges, and inadequate concrete work on the roads. Only a few days remain until Ganeshotsav, and it has cautioned that the roads need to be fixed beforehand; otherwise, a significant protest will take place. In this context, during a meeting with Mahendra Kini, Executive Engineer of the Public Works Department in Palghar, he inquired about the dire state of the road while presenting a statement.
Even after nearly ten years since Palghar district was formed, it has not experienced comprehensive growth. In spite of several development projects such as the Bullet Train, Mumbai-Baroda Expressway, Vadhan Port, Murbe Jetty, Mumbai-Ahmedabad Highway, and the recently-launched Reliance Textile Park initiative, the district still remains in poor condition.
Students, emergency vehicles, and everyday people are experiencing significant hardship because of the bad state of the roads. Consequently, district leaders Ajay Thakur and Anup Patil have cautioned that Shiv Sena will initiate a vigorous demonstration if the potholes remain unfixed before Ganeshotsav according to a report by media.
At this time, a thorough conversation took place regarding the Udhwa Dhundalwadi road, roadways in the Chinchani region, potholes on the Safale-Varai road, and the perilous state of the Pargaon Bridge.
The holdup in pouring concrete for the Mumbai-Ahmedabad highway is creating significant traffic jams. Residents are spending four to five hours traveling to Mumbai, and the frequency of accidents and fatalities has risen. Hence, the Pal family has requested Union Minister Nitin Gadkari to allow the concreting to proceed and re-tarmac
Maharashtra
Maharashtra: Shiv Sena MP Ravindra Waikar Demands Special Column For Orphaned Children In 2027 Census

Mumbai: Raising concerns over the growing number of orphaned children in the country, Shiv Sena (Shinde faction) MP from Mumbai North-West, Ravindra Waikar, on Wednesday urged the government to include a special column for orphans in the upcoming 2027 Census. He made this demand in the Lok Sabha under Rule 377, drawing the attention of the House to the issue.
Waikar said that according to UNICEF data, India has nearly 2.5 crore orphaned children, many of whom lack any form of support. Despite being one of the largest population surveys in the world, the national census has so far failed to record the number of such children. He reminded the House that the Supreme Court had earlier expressed concern over the increasing number of orphaned children and directed states to conduct surveys to identify them.
The court had also emphasized that these children must receive all benefits guaranteed under the Right to Education (RTE) Act. “Including a special column for orphaned children in the 2027 Census, as suggested by the Supreme Court, will ensure that they are identified and provided with their rightful access to education and welfare schemes. It is both a moral and constitutional responsibility to secure their future,” Waikar said in his submission.
The proposal, tabled through the Lok Sabha Speaker, stressed that only through accurate enumeration in the Census can the government effectively plan policies to safeguard the lives and futures of orphaned children.
Maharashtra
Maharashtra Govt To Fund 50% Of 268 New AC Rakes For Mumbai Suburban Rail Services, Skips Loan Route

Mumbai: In a major development, the state has decided to exclude the component of purchasing new AC rakes for Mumbai Suburban Services from the Mumbai Urban Transport Project III and III-A. Instead of availing a loan, the state will bear 50 per cent of the cost, amounting to Rs 2413 crore, for purchasing 268 new AC rakes by disbursing the amount from its annual budget.
Earlier, while signing the agreement for the implementation of the MUTP III and 3A with the central government, the state was supposed to raise the required funds through a loan. For the MUTP III, the state and the centre have raised Rs 3500 crore through a loan from the Asian Infrastructure Investment Bank (AIIB), which will be repaid on a 50:50 sharing basis. For the MUTP III-A, Rs 33,690 crore needed to be raised equally by the centre and the state.
Now, the state has, in consultation with the central government, decided to exclude the part of procuring new AC rakes by availing loans and instead will bear 50 per cent of the total cost of the 268 AC rakes, sources in the know of the developments. The state can make the required provision in its annual budget for the coming years, as the new ranks will take some time, sources said.
Approval Given
On Tuesday, the cabinet committee on infrastructure gave its approval, and the proposal was forwarded to the central government for necessary approval. It might take a few months, and the central government will also make available its share, added the sources. The total cost of the MUTP III-A, approved by the state government in 2018, is huge considering the gamut of the projects, which includes development of new stations, new rakes, 3rd and 4th line between Kalyan and Badlapur, 5th and 6th line between Borivali and Virar, 4th lane between Kalyan and Asangaon, extending the harbour line between Goregaon and Borivali, remodelling of Kalyan Junction to separate the main line and the suburban line etc.
The cost of the MUTP III-A is expected to be shared by Brihanmumbai Municipal Corporation (BMC), Navi Mumbai Municipal Corporation, CIDCO and MMRDA as well. The project has achieved just 6 per cent physical progress to date. On the other hand, the MUTP III has achieved 42 per cent, and the MUTP II has achieved 87 per cent physical progress.
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