Maharashtra
Mumbai startup develops India’s first universal gene test for infectious disease
Mumbai-based health-tech startup HaystackAnalytics has developed the first of its kind universal infectious diseases (ID) gene test to identify existing and emerging infections, the company said on Monday.
The company is supported by the Department of Science and Technology, as well as several private healthcare players.
To identify infections, the company deploys Next-Generation Sequencing (NGS) technology and Artificial Intelligence (AI), and also provides information on drug resistance to support and identify correct treatment options for patients.
The new Universal Infectious Diseases test will be rolled out with their current partners in a phased manner over the next three months, the company said in a statement.
It will initially be targeted at identifying and treating sepsis in Intensive Care Unit (ICU) patients, but gradually be made available to anyone suffering from a fever of unknown origin, by eradicating the need to conduct multiple tests.
The test comes at an opportune time, as Covid-19 pandemic highlights the need for better diagnostic technologies, appropriate antibiotic use, and the renewed importance of infection prevention strategies.
“The test enables rapid (within hours) and comprehensive (covering nearly all known bacterial and fungal pathogens) screening in a near to point of care deployment. Leveraging the power of next generation sequencing and AI, the team of scientists and engineers at Haystack has been able to eliminate the need for a redundant and expensive battery of tests, with a single test,” Dr. Anirvan Chatterjee, Co Founder and CEO of HaystackAnalytics, said.
“Our single point focus is to prevent each and every death caused due to treatable infections. Genomics has the potential to reduce trial and error in disease management and bring equality of access to high quality healthcare,” he added.
In the past, HaystackAnalytics had partnered with various diagnostic centers and over 20 hospitals including AIIMS, to introduce their sequencing-based clinical products for Tuberculosis and Covid in the past.
It is while working on two of the most debilitating infectious diseases — Tuberculosis and Covid — the company said it recognised the true burden of inaccurate diagnosis of infections in India and the world.
While the novel coronavirus infected and killed millions of people across the globe, there are various other infectious diseases that continue to plague India.
In particular, India accounts for the largest number of sepsis cases (11.3 million) and sepsis-related deaths (2.9 million) in the world, as per a global study published in the Lancet in 2020.
Despite having a wide range of antibiotics and antifungal medicines, sepsis is a life-threatening organ failure. It occurs when the body ends up injuring its own tissues and organs, in response to an infection, leading to shock, disability, multi-organ failure, and even death if left untreated in the early stages.
“A large proportion of these deaths can be avoided by early and accurate identification of the pathogen causing the infection. Haystack’s UID test has been developed to solve this exact problem,” Chatterjee said.
Maharashtra
MVA protest march in Nagpur seeks HM Amit Shah’s apology for remarks on B.R. Ambedkar
Nagpur, Dec 19: The Opposition Maha Vikas Aghadi (MVA) in Maharashtra took out a vociferous protest march here on Thursday to condemn and demand an apology from Union Home Minister Amit Shah for his remarks on B.R. Ambedkar in the Parliament.
The MVA constituents, Congress-Shiv Sena (UBT)-Nationalist Congress Party (SP) leaders gathered and joined the long procession from the Constitution Square to the Legislature Building.
They were carrying banners, placards, pictures of B.R. Ambedkar, some sporting copies of the Indian Statute, and raised angry slogans against HM Shah and the Bharatiya Janata Party (BJP).
Sporting dark blue caps, bands or shawls with the words ‘Jai Bhim’ printed, the top MVA leaders including SS (UBT)’s Leader of Opposition (Council) Ambadas Danve, SS (UBT) Group Leader Aditya Thackeray, Congress’ ex-Leader of Opposition Vijay Wadettiwar, NCP (SP)’s state chief Jayant R. Patil, Rohit R. Pawar and other leaders, plus Opposition legislators squarely hit out at HM Shah’s remarks and ranted cries for his apology.
The MVA leaders hailed the virtues of B.R. Ambedkar for giving India a Constitution that has equal rights to all the citizens, uplifted the poor and downtrodden, acknowledged his contributions for the depressed classes and hailed his services to the nation, while vowing that “the country will never tolerate any insults” to him.
Simultaneously, B.R. Ambedkar’s grandson, Prakash Ambedkar-led Vanchit Bahujan Aghadi (VBA) also organised separate agitations in Pune and other places to flay HM Shah.
SS (UBT) President Uddhav Thackeray and other leaders have urged Prime Minister Narendra Modi to sack HM Shah from the Cabinet.
Earlier, the participants bowed, garlanded and saluted a life-size statue of B.R. Ambedkar, paid homage and then launched the march which terminated outside the Vidhan Bhavan where the Winter Session is currently underway and continued to raise slogans against the ruling BJP.
It may be recalled that a couple of days ago, HM Shah had made certain remarks pertaining to B.R. Ambedkar which the Opposition termed as ‘disrespectful’, and went on to spark an outrage in the state and different parts of the country.
However, HM Shah has claimed that his statement was twisted out of context and he turned around to blame the Congress terming it as ‘anti-Ambedkar’ and against the Dalits.
Maharashtra
Indian Navy-ferry disaster: Hunt on for 2 more feared missing in Arabian Sea
Mumbai, Dec 19: The search and rescue operations resumed on Thursday morning to trace out at least two tourists still ‘missing’ after an Indian Navy speedboat crashed into a passenger ferry off the Gateway of India in the Arabian Sea on Wednesday evening claiming 13 lives, including that of four naval personnel, officials said.
In one of the worst-ever maritime disasters around Mumbai, 13 people were killed while another 105 were rescued when the chockful ferry, ‘Neelkamal’ was going from Gateway of India to Elephanta Isles, the famed UNESCO World Heritage site and was hit by the Navy speedboat.
An official said that the Indian Navy, Marine Police and other agencies have deployed their vessels to search for the two persons who were thrown into the waters after the deadly collision in mid-sea, around 5 kms from the Gateway of India, in the water channel near the tiny Butcher Island oil terminal.
The Indian Navy officially said that one of its speedboats which was on engine trials developed a snag, the pilot lost control and rammed with full force into the tourist boat, as chilling videos of the incident surfaced late last night.
The passenger boat, a private catamaran named ‘Neelkamal’, was ferrying more than 100 tourists plus five crew members when the disaster struck like a bolt from the blue, around 4 P.M.
Official sources said that the Navy’s rigid inflatable boat undergoing engine trials crashed into the ‘Neelkamal’ at high speed, overturning it and throwing most of the tourists into the sea near Karanja on the Raigad coast, around 10 kms from the origin point, Gateway of India.
The owner of the vessel, Rajendra Padte, said that the ‘Neelkamal’ had departed on its regular voyage to Elephanta Islands around 3.15 P.M and barely a couple of minutes later the tragedy was reported, “but it was not our fault”.
Peasants & Workers Party of India (PWP) General Secretary and ex-legislator Jayant P. Patil, who was present at the spot slammed the concerned authorities for the massive tragedy with the ‘Neelkamal’ sinking soon afterwards.
President Droupadi Murmu, Prime Minister Narendra Modi, Defence Minister Rajnath Singh, Chief Minister Devendra Fadnavis plus several Opposition leaders condoled the tragedy and the loss of innocent lives.
The PM announced an ex-gratia of Rs 2 lakh and the CM announced a compensation of Rs 5 lakh to the kin of each deceased, plus financial assistance to all the injured.
A civic official said that the JNPA Hospital has admitted 57 people, 24 in the Naval Dockyard medical facility, one in INHS Ashvini Hospital, 13 in INHS Sanghani (Karanja), 10 in St. George Hospital, and 12 in a hospital on the mainland at Karanja, plus around 8 who recovered have been discharged from the concerned hospitals.
Maharashtra
Mumbai: 3 Feared Dead After Ferry Travelling From Gateway Of India To Elephanta Island Capsizes
Mumbai: In a shocking incident, a ferry which was travelling from Mumbai’s Gateway of India to Elephanta Island started sinking in the Arabian Sea on Wednesday. There are reports that around 30 passengers onboard the ferry when the incident occurred. Rescue operation is being carried and the passengers are being taken out from the sinking boat.
As per reports, the boat named Neelkamal was traveling with 30 to 35 passengers onboard. Currently, a rescue operation is underway by the defense forces. Neelkamal ferry boat was hit by the Pilot vessel at stern which led to the capsize of the boat. The incident occurred near Uran, Kunja.
As per reports, another speed boat which is said to be a patrolling boat collided with the ferry from behind due to which the ferry capsized. The collision led to the boat overturning, with around 50 passengers onboard. Rescue operations were immediately launched in coordination with the Navy, Coast Guard, and Marine Police.
A total of 15 boats have been deployed in the area, including 11 Navy boats, 3 Marine Police boats, and 1 Coast Guard boat. Additionally, four helicopters are actively conducting search and rescue (SAR) missions to locate and assist survivors. So far, 66 people have been rescued from the waters. Unfortunately, three casualties have been confirmed, with their bodies recovered. The exact number of missing persons and potential casualties remains uncertain as the rescue efforts continue.
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