Maharashtra
Mumbai startup develops India’s first universal gene test for infectious disease
Mumbai-based health-tech startup HaystackAnalytics has developed the first of its kind universal infectious diseases (ID) gene test to identify existing and emerging infections, the company said on Monday.
The company is supported by the Department of Science and Technology, as well as several private healthcare players.
To identify infections, the company deploys Next-Generation Sequencing (NGS) technology and Artificial Intelligence (AI), and also provides information on drug resistance to support and identify correct treatment options for patients.
The new Universal Infectious Diseases test will be rolled out with their current partners in a phased manner over the next three months, the company said in a statement.
It will initially be targeted at identifying and treating sepsis in Intensive Care Unit (ICU) patients, but gradually be made available to anyone suffering from a fever of unknown origin, by eradicating the need to conduct multiple tests.
The test comes at an opportune time, as Covid-19 pandemic highlights the need for better diagnostic technologies, appropriate antibiotic use, and the renewed importance of infection prevention strategies.
“The test enables rapid (within hours) and comprehensive (covering nearly all known bacterial and fungal pathogens) screening in a near to point of care deployment. Leveraging the power of next generation sequencing and AI, the team of scientists and engineers at Haystack has been able to eliminate the need for a redundant and expensive battery of tests, with a single test,” Dr. Anirvan Chatterjee, Co Founder and CEO of HaystackAnalytics, said.
“Our single point focus is to prevent each and every death caused due to treatable infections. Genomics has the potential to reduce trial and error in disease management and bring equality of access to high quality healthcare,” he added.
In the past, HaystackAnalytics had partnered with various diagnostic centers and over 20 hospitals including AIIMS, to introduce their sequencing-based clinical products for Tuberculosis and Covid in the past.
It is while working on two of the most debilitating infectious diseases — Tuberculosis and Covid — the company said it recognised the true burden of inaccurate diagnosis of infections in India and the world.
While the novel coronavirus infected and killed millions of people across the globe, there are various other infectious diseases that continue to plague India.
In particular, India accounts for the largest number of sepsis cases (11.3 million) and sepsis-related deaths (2.9 million) in the world, as per a global study published in the Lancet in 2020.
Despite having a wide range of antibiotics and antifungal medicines, sepsis is a life-threatening organ failure. It occurs when the body ends up injuring its own tissues and organs, in response to an infection, leading to shock, disability, multi-organ failure, and even death if left untreated in the early stages.
“A large proportion of these deaths can be avoided by early and accurate identification of the pathogen causing the infection. Haystack’s UID test has been developed to solve this exact problem,” Chatterjee said.
Maharashtra
Shiv Sena wave in North Maharashtra, Dr. Shrikant Shinde takes charge of election campaign

Mumbai Nandurbar: Shiv Sena is on a wave in North Maharashtra. A large number of “Ladli Bheenas” and youth are participating in the rallies of Shiv Sena youth leader Dr. Shrikant Shinde. Dr. Shinde launched his election campaign in North Maharashtra today. Addressing the gathering, he said that the Mahayoti government has taken strong steps to empower women and youth, which is why Maharashtra’s Ladli Behna Yojana is becoming self-reliant. Attacking the opposition, he said that many opposition leaders were opposing the “Ladli Behna Yojana” but under the leadership of Deputy Chief Minister Eknath Shinde, this scheme was implemented and it will not be stopped under any circumstances. The opposition is only spreading confusion, Ladli Behna will respond with their votes. Dr. Shrikant Shinde explained that in the last three years, Shiv Sena has reached every corner of Maharashtra under the leadership of Eknath Shinde. Shinde Sahib is empowering his workers by holding eight meetings every day. He has an Urban Development Department, which has resulted in record-breaking funding for the backward villages of Maharashtra, paving the way for strong rural development.
Dr. Shrikant Shinde criticized UBT and said that some people are experts in criticizing, but they have never done any concrete work for the people. That is why today Mahayoti candidates are seen everywhere. The people are well aware of the state of the opposition.
Maharashtra
Kalyan College Namaz Controversy: SIO Demands Action Against Perpetrators

Mumbai: SIO has demanded strict action against the hooliganism of Bajrang Dal and Vishwa Hindu Parishad on offering prayers in Mumbai’s Kalyan College. Here, State Secretary SIO Aziz Ahmed said that
The incident that took place at Ideal College of Pharmacy and Research in Kalyan is highly condemnable and unacceptable, where hooligans belonging to Bajrang Dal entered the college campus, threatened and harassed Muslim students for offering prayers and even tried to make them sit in front of the statue of Chhatrapati Shivaji Maharaj. This incident is a direct attack on religious freedom and the sanctity of the educational campus.
SIO strongly condemns this incident and expresses complete solidarity with the affected students. We demand that strict action be taken against the accused at the earliest, the college administration ensure the safety of the students and take concrete steps to prevent such incidents in the future.
We appeal to the entire student community to maintain religious harmony and remain united against such sectarian attitudes and demonstrate strong solidarity.
Maharashtra
Five-year-old kidnapped girl rescued from Vakola, five arrested, girl held hostage by uncle in Panol

Mumbai: Police has claimed to have arrested five accused, including uncle Momani, on charges of kidnapping a five-year-old girl. The gang had planned to kidnap and sell the girl. A case of kidnapping of a minor girl was registered on November 22 under the limits of Vakola police station. Several teams were formed in Zones 8 and 7. During the investigation, it was revealed that a suspicious rickshaw had gone to Panvel and returned. A man, a woman, a rickshaw driver and the girl were in the rickshaw between 2 and 3 am. The kidnappers were identified as the girl’s uncle Lawrence Niconelis Fernandes, 42, and his wife Momani, who is a Mangal degree, both of them had gone to Panvel by rickshaw and were going to sell the kidnapped girl. The kidnapped girl was recovered from the possession of their acquaintance Sans. The Sans gave details about the wanted accused during the investigation, after which Windra Dinesh Chavan, 60, and Anjali Ajit Korgaokar, 57, were arrested from New Panvel, Raigad. The kidnapped girl was sold for Rs 1,80,000 and Vrinda Chavan was taken into custody from her house and the girl was safely brought to Vakola. This operation was carried out by DCP Manish Kalwaniya on the instructions of Mumbai Police Commissioner Deven Bharti and the girl was recovered safely. In this case, the police have arrested rickshaw driver Latif Abdul Majeed Sheikh, 52, a resident of Santa Cruz, Lawrence Nicholas Fernandes, 42, a laborer from Raigarh, Mangal Dagra Jadhav, 38, from Raigarh, Kiran Maruti Sons, 38, from Panvel, Vrinda Vanish Chavan, 60, from Raigarh and the investigation is underway.
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