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Mumbai startup develops India’s first universal gene test for infectious disease

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Mumbai-based health-tech startup HaystackAnalytics has developed the first of its kind universal infectious diseases (ID) gene test to identify existing and emerging infections, the company said on Monday.

The company is supported by the Department of Science and Technology, as well as several private healthcare players.

To identify infections, the company deploys Next-Generation Sequencing (NGS) technology and Artificial Intelligence (AI), and also provides information on drug resistance to support and identify correct treatment options for patients.

The new Universal Infectious Diseases test will be rolled out with their current partners in a phased manner over the next three months, the company said in a statement.

It will initially be targeted at identifying and treating sepsis in Intensive Care Unit (ICU) patients, but gradually be made available to anyone suffering from a fever of unknown origin, by eradicating the need to conduct multiple tests.

The test comes at an opportune time, as Covid-19 pandemic highlights the need for better diagnostic technologies, appropriate antibiotic use, and the renewed importance of infection prevention strategies.

“The test enables rapid (within hours) and comprehensive (covering nearly all known bacterial and fungal pathogens) screening in a near to point of care deployment. Leveraging the power of next generation sequencing and AI, the team of scientists and engineers at Haystack has been able to eliminate the need for a redundant and expensive battery of tests, with a single test,” Dr. Anirvan Chatterjee, Co Founder and CEO of HaystackAnalytics, said.

“Our single point focus is to prevent each and every death caused due to treatable infections. Genomics has the potential to reduce trial and error in disease management and bring equality of access to high quality healthcare,” he added.

In the past, HaystackAnalytics had partnered with various diagnostic centers and over 20 hospitals including AIIMS, to introduce their sequencing-based clinical products for Tuberculosis and Covid in the past.

It is while working on two of the most debilitating infectious diseases — Tuberculosis and Covid — the company said it recognised the true burden of inaccurate diagnosis of infections in India and the world.

While the novel coronavirus infected and killed millions of people across the globe, there are various other infectious diseases that continue to plague India.

In particular, India accounts for the largest number of sepsis cases (11.3 million) and sepsis-related deaths (2.9 million) in the world, as per a global study published in the Lancet in 2020.

Despite having a wide range of antibiotics and antifungal medicines, sepsis is a life-threatening organ failure. It occurs when the body ends up injuring its own tissues and organs, in response to an infection, leading to shock, disability, multi-organ failure, and even death if left untreated in the early stages.

“A large proportion of these deaths can be avoided by early and accurate identification of the pathogen causing the infection. Haystack’s UID test has been developed to solve this exact problem,” Chatterjee said.

Maharashtra

Maharashtra Urdu Academy should be formed, funds and staff should be appointed for the promotion of Urdu language Abu Asim Azmi

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Mumbai: Mumbai Maharashtra Legislative Assembly member Abu Asim Azmi has demanded the immediate formation of Urdu Academy to promote Urdu. He said that academies of other languages ​​including Gujarati and Marathi are active, but the condition of Urdu Academy is pathetic. Earlier there were 25 employees in this academy, but now only the superintendent is left. The remaining 24 have retired. The government needs to pay attention to the plight of Urdu.

The formation of this academy will promote Urdu. Azmi demanded that the Urdu Academy is facing difficulties due to the provision of funds. He said that the government allocates Rs 1 crore on paper, but this fund is not provided. Abu Asim Azmi said that Urdu is the language of our country. Whenever the Chief Minister or any other minister speaks in the House, they resort to Urdu poetry. But when it comes to the establishment of Urdu Academy and the development of Urdu language, the government is doing injustice

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On the third day of Maharashtra Assembly, the opposition protested against the corruption of Rs 3000 crore.

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Mumbai: On the third day of Maharashtra Assembly in Mumbai, the opposition accused the ruling party of corruption and protested on the stairs of Vidhan Bhavan, accusing the government of giving contracts to every company of its choice. The state’s construction and development department has given a contract of Rs 3000 crore to Mahagathbandhan government’s Megha Engineering Company. Many shortcomings have been found in the work of this company, but despite this it is dear to the government. Therefore, slogans were raised on the stairs of Vidhan Bhavan that giving contract to this company is condemnable. Opposition members were also holding banner posters of contractor Megha Engineering, in which the picture of the owner of Megha Company was also visible. The opposition has intensified its protest against corruption in the Mahagathbandhan government. Shiv Sena opposition leader Ambadas Danve, Congress members and all parties including Congress protested loudly on the stairs of Vidhan Bhavan and drew the attention of the government towards this.

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Maharashtra

Mumbai School Teacher Arrested Under POSCO Act For Sexually Assaulting Minor Student Multiple Times Over One Year

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Mumbai: A horrifying case has come forward from a well-known Mumbai school where a 40-year-old English teacher from a renowned Mumbai school was arrested under the POCSO Act for allegedly sexually assaulting a 16-year-old student multiple times over a year.

The attacks began after the teacher developed an attraction to the boy while organising dance groups for the school’s annual function in December 2023. Initial advances made in January 2024 were rebuffed by the student, prompting the teacher to enlist a friend to persuade him, claiming such relationships were common. Following this, the teacher picked the boy up, took him to a secluded location, and assaulted him.

According to a report by media, in the ensuing weeks, the teacher provided the student with anti-anxiety medication and arranged outings to luxury hotels, where they had several sexual encounters, often intoxicating him beforehand. The teacher’s arrest has shocked the school community.

The student’s behavioral changes raised concerns with his family, but they decided against reporting the incidents, hoping it would resolve on its own as he neared graduation. After leaving school earlier this year, the student fell into depression, and the situation escalated when the teacher attempted to contact him through the domestic staff. This prompted the family to file a complaint with the police.

Authorities have charged the teacher with penetrative sexual assault and related offenses under the POCSO Act and other relevant laws. The case underscores serious issues concerning student abuse within educational institutions. The teacher has been remanded in police custody until Wednesday, as investigations continue into this disturbing incident involving a minor.

Similar Incident

In another incident a mathematics teacher in Sirmaur district of Himachal Pradesh was arrested for allegedly sexually harassing 24 girl students in classes VIII to X last week. Complaints to the principal led to the teacher’s suspension and subsequent police custody. The Director of School Education initiated an inquiry due to the seriousness of the situation, tasking the Deputy Director of Elementary Education with gathering information promptly. The teacher now faces charges under Section 75 of the Bharatiya Nyaya Sanhita and POCSO provisions, reflecting the education department’s urgency in addressing these allegations.

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