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Mumbai Reports 1st Death Due To GBS Virus; All You Need To Know About Central Govt’s Guidelines To Control Outbreak

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Mumbai: Mumbai reported its first death due to Guillain-Barré Syndrome (GBS) on Wednesday. A 53-year-old resident of Wadala, who worked at the Brihanmumbai Municipal Corporation’s BN Desai Hospital passed away after battling GBS. The patient was receiving treatment at Nair Hospital in Mumbai, where he ultimately succumbed to the illness.

In Pune, Guillain-Barré Syndrome (GBS) has been actively affecting residents. A 37-year-old driver from Pune recently passed away due to GBS. The number of suspected and confirmed GBS cases in Pune has risen to 197, with five new cases reported.

As of yesterday, there were 192 reported cases of GBS, with 39 patients from the Pune Municipal Corporation area, 91 from newly added villages in the civic region, 29 from Pimpri Chinchwad, 25 from the rural Pune area and eight from other districts. Today, Pune has reported 5 new GBS cases bringing the total to 197, while the death toll remains at 7.

GBS Management in Maharashtra

With the rise in cases of Guillain-Barré syndrome (GBS) in Maharashtra, the Central government recently issued guidelines for the people of the state.

According to public health officials on Thursday, a high-level, multidisciplinary team from the Union Ministry of Health and Family Welfare has provided the GBS guidelines to the state government.

Press Release Issued on January 27, by Ministry of Health and Family Welfare

The guidelines state that the Ministry has deployed a multi-disciplinary team to Pune, Maharashtra, to assist state health authorities in implementing public health measures and managing the growing number of suspected and confirmed GBS cases in the area.

The central team includes seven experts from the National Center for Disease Control (NCDC) Delhi, NIMHANS Bengaluru, the Regional Office of Health & Family Welfare and the National Institute for Virology (NIV), Pune. Three NIV experts had already been supporting local authorities, and the team has now been expanded.

The team will work closely with the state health departments to assess the situation on the ground and provide recommendations for necessary public health actions. The Union Health Ministry is actively monitoring the situation and coordinating with the state.

Deputy Director of Health Services and Rapid Response Team (RRT) who is managing the GBS situation. Dr.Radhakishan Pawar stated, “The guidelines are detailed and focus primarily on patient management. These will be shared with all local bodies, including the Pune and Pimpri Chinchwad Municipal Corporations, Pune Rural, and other local authorities across the state.”

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India takes lead in extreme heat risk management under PM Modi’s leadership

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New Delhi, June 7: India has taken a proactive and forward-thinking approach to extreme heat risk management under the leadership of Prime Minister Narendra Modi, said Dr PK Mishra, Principal Secretary to the Prime Minister.

Delivering the keynote address during the Special Session on Extreme Heat Risk Governance in Geneva, he underlined that rising temperatures posing a systemic risk to public health, economic stability, and ecological resilience.

“India welcomes the United Nations Office for Disaster Risk Reduction’s (UNDRR) initiative to advance the Common Framework for Extreme Heat Risk Governance as a platform for shared learning, guidance, and collaboration,” he told the gathering, according to a Prime Minister’s Office (PMO) statement on Saturday.

Dr Mishra pointed out that India has moved beyond disaster response toward integrated preparedness and mitigation strategies. Since 2016, the National Disaster Management Authority (NDMA) has developed comprehensive national guidelines on heatwave management, revised in 2019, which laid the foundation for decentralised Heat Action Plans (HAPs).

He acknowledged the pioneering ‘Ahmedabad Heat Action Plan’, which demonstrated how early warnings, inter-agency coordination, and community outreach can save lives.

“Over 250 cities and districts across 23 heat-prone states have operational Heat Action Plans, supported by NDMA’s advisory, technical, and institutional mechanisms”, said the Principal Secretary, underscoring that strengthened surveillance, hospital readiness, and awareness campaigns have significantly reduced heatwave-related mortality.

India’s approach is whole-of-government and whole-of-society, engaging ministries from health, agriculture, urban development, labour, power, water, education, and infrastructure.

“Extreme heat deeply impacts communities, and India has actively incorporated traditional wisdom and local experiences into its response”, said Dr Mishra.

He noted that schools have become catalysts for behavioural change, educating children about climate resilience. He also emphasised that hospitals and primary health centres must be strengthened to ensure swift and effective emergency responses.

Outlining India’s transition from a preparedness-only approach to long-term heatwave mitigation, including cool roof technologies, passive cooling centres, urban greening, and the revival of traditional water bodies, Mishra affirmed that India is integrating Urban Heat Island (UHI) assessments into city planning.

He called for a global focus on developing a localised heat-humidity index based on real-time data to enhance early warning systems, advancing building technologies and passive cooling innovations that are affordable and culturally appropriate and addressing equity concerns, as extreme heat disproportionately affects women, outdoor workers, the elderly, and children.

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Study shows how Covid virus shields itself during replication

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New Delhi, June 6: US researchers have identified a mechanism that SARS-CoV-2 — the virus that causes Covid-19 — uses to protect itself inside the body as it works to replicate and infect more cells.

Without this protective mechanism, viral infection is dramatically reduced, said the team from the Texas Biomedical Research Institute and the University of Chicago.

The finding, published in the journal Nature Communications, not only provides a potential target for new Covid therapies but also offers insights that could inform future vaccine and antiviral development.

The study builds on earlier work from Texas Biomed that identified ORF3a, a type of viral protein most important for the virus’s pathogenicity, or ability to cause disease.

Specifically, the team found that SARS-CoV-2 ORF3a appears to play a vital role in protecting structural proteins, most notably the spike protein that facilitates spread into other cells, as they are assembled on the surface of viral particles.

It does this by driving the formation of a dense group of proteins that surround the spike protein and provide protection while in transit, much like security detail protecting a person or an armoured vehicle carrying cash to the bank, the researcher said.

Jueqi Chen, Assistant Professor at the University of Chicago, termed these protective complexes “3a dense bodies” or 3DBs for short.

It appears that 3DBs help prevent the spike protein from being cut into smaller components.

When ORF3a is missing, these 3DBs fail to form, and the spike protein often arrives damaged, severely impairing the nascent virus’s ability to infect new cells, the expert said.

“ORF3a could therefore be a good target for drugs to block the virus,” said Luis Martinez-Sobrido, Professor at Texas Biomed.

“This discovery could also be instrumental for vaccine development, as we illustrated previously,” Martinez-Sobrido added.

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World Environment Day: Ministers call to stop plastic pollution, embrace sustainability

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New Delhi, June 5: Union Ministers on World Environment Day on Thursday urged citizens to put an end to plastic pollution and embrace sustainability while also planting more trees for a greener and cleaner future.

World Environment Day is observed every year on June 5. The theme this year, ‘Beat Plastic Pollution’ aims to end plastic pollution.

“As we mark #EnvironmentDay today, let’s reaffirm our commitment to protecting our planet and ensuring sustainability for all living beings. Always remember nature protects when protected,” said Bhupender Yadav, Union Minister for Environment, Forest and Climate Change (MoEFCC), in a post on social media platform X.

“On World Environment Day, let us renew our commitment to protect the planet by planting more trees, reducing pollution, conserving resources, and embracing sustainability. Together, our small steps can create a greener, healthier, and more hopeful future for all,” added Pralhad Joshi, Union Minister of Consumer Affairs.

Globally, an estimated 11 million tonnes of plastic waste leak into aquatic ecosystems each year, while microplastics accumulate in the soil from sewage and landfills, due to the use of plastics in agricultural products.

Jitendra Singh, Union Minister of State (Independent Charge) for Science and Technology stated that India “reiterates its strong commitment to beat plastic pollution through proactive policies, sustainable practices and mass awareness. Together, let’s restore ecosystems, conserve biodiversity, and build a greener, cleaner future”.

“Let us take a pledge on this Environment Day – stop plastic pollution, live in harmony with nature, and create a greener, cleaner, and safer earth for future generations,” added Kirti Vardhan Singh, Union Minister of State for MoEFCC.

Besides choking the planet, plastic pollution permeates even our bodies in the form of microplastics and poses several health risks.

“Plastic pollution is choking our planet – harming ecosystems, well-being, and the climate. Plastic waste clogs rivers, pollutes the ocean, and endangers wildlife,” said UN Secretary-General António Guterres.

“And as it breaks down into smaller and smaller parts, it infiltrates every corner of Earth: from the top of Mount Everest to the depths of the ocean; from human brains; to human breastmilk,” he added, calling for a movement for urgent change.

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