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Corbevax booster gives maximum protection, reveals Hyd hospital study

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 Amidst concerns of a new Covid wave in India following massive surge in China and other countries, research at AIG Hospitals here has revealed that Corbevax booster in individuals vaccinated with Covishield gives maximum protection against Omicron variants.

The scientific study has proved the immunity benefits of indigenous heterologous vaccine booster, Corbevax in combating Omicron variants.

The study titled “Heterologous booster dose with Corbevax following primary vaccination with Covishield enhances protection against SARS-CoV-2” has been published in the high-impact factor journal “Vaccines”.

Announcing the findings of the study, AIG Hospitals Chairman Dr D Nageshwar Reddy told media persons that the study was done on 250 healthcare workers who had received 2 doses of Covishield as the primary vaccine regimen not more than 6 months ago. None of the participants had any adverse events following the administration of Corbevax booster dose.

“We knew from our previous studies that mixed vaccines produce better immune response; therefore, when the government approved Corbevax to be given as a heterologous booster to individuals already vaccinated with Covishield, our aim was to determine how a different vaccine platform (protein-based) will impact the immune response especially in context of the Omicron variant,” he said.

Corbevax is an indigenously developed peptide-based vaccine which is different from the viral vector (Covishield) or the inactivated vaccine (Covaxin). The key difference is that Corbevax uses only a protein subunit of the virus replicated inside a yeast cell while the others are whole virus vaccines. The advantage of peptide-based vaccine is that it considerably reduces the risks of allergic and autoimmune responses making them safe for widespread usage.

Dr Reddy said the results further cemented their belief that mixed vaccines are absolutely safe. “The second aspect of the study was to measure the antibody response as well as the T-cell (memory cell) response at 30 days and then at 90 days to correctly estimate the overall protection against the circulating Omicron variant.

When estimating the effectiveness of a vaccine, both the antibody response and T-cell (Memory cell) response are essential.

“In our study, we compared the immune responses among those individuals who were given the same vaccine, i.e., Covishield (homologous group) as a booster and those who were given Corbevax as a booster (heterologous group). The S1/S2-spike protein IgG antibody levels and T/B Cell response of these groups were compared at 30 days and at 90 days. While the homologous and heterologous groups showed increased S1/S2-spike protein IgG antibody level at 30 days, the heterologous group (Corbevax as a booster) showed higher levels of antibodies at both 30 days and 90 days,” Dr Reddy said.

The study was undertaken when Omicron variants are circulating in India; therefore, it would be appropriate to say that heterologous booster (Corbevax) would be effective in combating any wave that is fueled by sub-variants of the Omicron.

High-risk group people should consider taking the booster dose and continue to take Covid appropriate precautions all the time especially when in public spaces.

Replying to queries, Dr Reddy said if a person has taken Covaxin double dose, he should also take Corbevax as the booster dose. “The booster dose should be from the other company as this gives more protection,” he said.

He noted that only 28 per cent of people in the country have taken booster dose. Corbevax is manufactured by Hyderabad-based Biological E.

Dr Reddy said that the vaccine is easy to manufacture and it is already available in the market at a price of Rs 250.

He suggested that China should also import Corbevax to save lives.

Dr Reddy also made it clear that there is no need for panic as the both the central and state governments are taking necessary measures and adequate stocks of vaccines and Remdesivir are available.

He believes that the number of Covid cases may increase over the next two months but from March next year, the situation will be normal.

He said people should wear masks while going in crowded places. He believes that the impact of the new variant of Omicron will not be severe.

Maharashtra

Senior IPS Officers Transferred in Maharashtra; Key Changes in Mumbai Police Leadership

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Mumbai: (By Kamar Ansari) In a major reshuffle within the Maharashtra Police, senior IPS officer Manoj Kumar Sharma, whose life inspired the Bollywood film 12th Fail, has been appointed as the new Joint Commissioner of Police (Law and Order), Mumbai.

Sharma, a 2005-batch IPS officer, has previously served as DCP Zone-1 and Additional Commissioner of Police (West Region) in Mumbai. He has also served with the Central Industrial Security Force (CISF). His appointment is being seen as a significant move in strengthening Mumbai’s law and order administration.

In another key transfer, Anil Kumbhare, who was serving as Joint CP (Traffic), has been appointed as the new Joint Commissioner of Police of the Crime Branch, Mumbai.

Senior IPS officer Rajesh Pradhan of the 2003 batch will now head the Economic Offences Wing (EOW), Mumbai.

Meanwhile, 2004-batch IPS officer Sussairaj Jayakumar, who was serving as Joint CP (Administration), Mumbai, has been appointed as the new Special Inspector General of Force-1, Maharashtra. Jayakumar has earlier served in Mumbai Police as DCP, Additional CP and Joint CP, and began his policing career as ASP in Malegaon.

Another senior officer, Satya Narayan Chaudhary, who was serving as Joint CP (Law and Order), has now been transferred as Joint CP (Traffic), Mumbai.

Additionally, 2004-batch IPS officer Pravin Padwal, who was serving as IG (Training), has been appointed as Inspector General of Police, Nashik Range.

The reshuffle is considered an important administrative move aimed at strengthening policing, crime control, traffic management and internal administration across Mumbai and Maharashtra Police departments.

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Maharashtra

Maha Vikas Aghadi should form a task force to revise voter lists in Maharashtra on the model of Bengal: Raees Sheikh

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Mumbai: A day after the Election Commission announced the Comprehensive Audit of Voter Lists (SIR) in Maharashtra, Samajwadi Party MLA from Bhiwandi East Raees Sheikh has urged Maha Vikas Aghadi (MVA) leaders to form a state-level task force to monitor the process and take steps to ensure that the incident of voter exclusion in West Bengal does not repeat itself. The SIR process led to the defeat of the Trinamool Congress in Bengal.

In a letter to Maharashtra Congress president Harshvardhan Sapkal, Shiv Sena leader and MP Sanjay Raut and Nationalist Congress Party (SP) state president Shashi Kant Shinde, MLA Raees Sheikh said that the Maha Vikas Aghadi should constitute a task force to guide voters, train Booth Level Agents (BLAs) and coordinate with the Election Commission. The SIR process in Bihar and West Bengal has resulted in the exclusion of a large number of voters, especially voters from tribal, Dalit, minority and weaker sections. 68 lakh voters in Bihar and 91 lakh voters in West Bengal have been excluded in this process. Maharashtra may face a similar situation if opposition parties do not take timely action. “In the recent West Bengal assembly elections, BJP won 95 seats while Trinamool Congress won 51 seats in constituencies where 25,000 voters were excluded during the SIR process, leading to TMC’s defeat,” MLA Raees Sheikh claimed. He added that under the SIR initiative, Booth Level Officers (BLOs) will visit voters’ homes between June 30 and July 29. “Voters will need help in completing the necessary documents, understanding the new voter registration process and the objection registration process. Booth Level Officers (BLAs) of all the allied parties and coordinating with the state Chief Electoral Officer and the Central Election Commission. Maha Vikas Aghadi must take immediate steps in this regard. Otherwise we will not be able to stop the ruling party’s vote rigging. The proposed state-level task force should include representatives of all allies in the alliance.”

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Maharashtra

Joint site inspection to be conducted to effectively implement mosquito control measures, Ashwini Bhide directs

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Various agencies in Mumbai should cooperate in providing access to the Pest Control Department team during site visits in mosquito control measures. Mosquito control measures should be effectively implemented by providing necessary support to the Pest Control Department in the Mumbai Municipal Corporation area. Besides, Municipal Corporation Commissioner Ashwini Bhide directed that the objective should be to reduce the number of patients through preventive measures against monsoon diseases by the Municipal Corporation.

A review meeting of the Mosquito Control Committee was held at the Municipal Corporation Headquarters today (14 May 2026) under the chairmanship of Mumbai Municipal Commissioner Ashwini Bhide.

. Additional Municipal Commissioner (Western Suburbs) Dr. Vipin Sharma, Deputy Commissioner (Municipal Commissioner’s Office) Prashant Gaikwad, Deputy Commissioner (Public Health) Sharad Uday, Executive Health Officer Dr. Daksha Shah, Pesticide Officer Amrit Suryavanshi were present in the meeting along with representatives of various government and semi-government organizations of Mumbai. Senior officers and representatives of government, semi-government organizations from Central Public Works Department, Mahada, Mumbai Metropolitan Region Development Authority, Mumbai Port Trust, Navy, Air Force, BEST, Postal Department, Mumbai Metro Rail Corporation Limited, Bhabha Atomic Research Centre, Dairy Department, Mahavataran, LIC, Airport Authority, Public Works Department, NTC attended the meeting. Obstacles in the access of the pest control team to places like dilapidated buildings, grassy areas, mill plots and containment areas of various agencies should be removed. There is a need to take mosquito control measures here with joint efforts. This will make it possible to control the increasing number of patients due to monsoon diseases. It has been observed that mosquito control measures have not been implemented for 6,160 water tanks in the premises of 21 agencies in the Mumbai Municipal Corporation area. A joint inspection visit should be organized in collaboration with the Pesticides Department of Mumbai Municipal Corporation and various agencies. Mumbai Municipal Corporation Commissioner Ashwini Bhide directed that various agencies should make joint efforts to implement preventive measures at mosquito breeding sites by May 31, 2026.

Training of over 5000 personnel at construction sites completed
Large-scale reconstruction of buildings is underway in the Mumbai Municipal Corporation area. Security officers and workers are being trained to implement mosquito control measures at construction project sites. More than 5000 personnel have been trained in mosquito control measures in the Mumbai Municipal Corporation area. A WhatsApp group has also been created for communication and coordination between security officers and the pest control department. As part of the monsoon measures, the pest control department has been conducting a drive since February to personally visit various establishments and inspect the covers installed on water tanks. During the inspection, it was observed that the covers of the water tanks were not in good condition and were not installed properly. It was also found that the work of removing obstructions and materials has not been completed. Engineering measures need to be implemented at some places. Various government and semi-government institutions have been directed to implement mosquito control measures before the monsoon through site visit campaigns. Municipal Corporation Commissioner Ashwini Bhide has directed that the mosquito control measures should be completed in a planned manner by 31 May 2026 through a joint campaign.

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