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Corbevax booster gives maximum protection, reveals Hyd hospital study

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 Amidst concerns of a new Covid wave in India following massive surge in China and other countries, research at AIG Hospitals here has revealed that Corbevax booster in individuals vaccinated with Covishield gives maximum protection against Omicron variants.

The scientific study has proved the immunity benefits of indigenous heterologous vaccine booster, Corbevax in combating Omicron variants.

The study titled “Heterologous booster dose with Corbevax following primary vaccination with Covishield enhances protection against SARS-CoV-2” has been published in the high-impact factor journal “Vaccines”.

Announcing the findings of the study, AIG Hospitals Chairman Dr D Nageshwar Reddy told media persons that the study was done on 250 healthcare workers who had received 2 doses of Covishield as the primary vaccine regimen not more than 6 months ago. None of the participants had any adverse events following the administration of Corbevax booster dose.

“We knew from our previous studies that mixed vaccines produce better immune response; therefore, when the government approved Corbevax to be given as a heterologous booster to individuals already vaccinated with Covishield, our aim was to determine how a different vaccine platform (protein-based) will impact the immune response especially in context of the Omicron variant,” he said.

Corbevax is an indigenously developed peptide-based vaccine which is different from the viral vector (Covishield) or the inactivated vaccine (Covaxin). The key difference is that Corbevax uses only a protein subunit of the virus replicated inside a yeast cell while the others are whole virus vaccines. The advantage of peptide-based vaccine is that it considerably reduces the risks of allergic and autoimmune responses making them safe for widespread usage.

Dr Reddy said the results further cemented their belief that mixed vaccines are absolutely safe. “The second aspect of the study was to measure the antibody response as well as the T-cell (memory cell) response at 30 days and then at 90 days to correctly estimate the overall protection against the circulating Omicron variant.

When estimating the effectiveness of a vaccine, both the antibody response and T-cell (Memory cell) response are essential.

“In our study, we compared the immune responses among those individuals who were given the same vaccine, i.e., Covishield (homologous group) as a booster and those who were given Corbevax as a booster (heterologous group). The S1/S2-spike protein IgG antibody levels and T/B Cell response of these groups were compared at 30 days and at 90 days. While the homologous and heterologous groups showed increased S1/S2-spike protein IgG antibody level at 30 days, the heterologous group (Corbevax as a booster) showed higher levels of antibodies at both 30 days and 90 days,” Dr Reddy said.

The study was undertaken when Omicron variants are circulating in India; therefore, it would be appropriate to say that heterologous booster (Corbevax) would be effective in combating any wave that is fueled by sub-variants of the Omicron.

High-risk group people should consider taking the booster dose and continue to take Covid appropriate precautions all the time especially when in public spaces.

Replying to queries, Dr Reddy said if a person has taken Covaxin double dose, he should also take Corbevax as the booster dose. “The booster dose should be from the other company as this gives more protection,” he said.

He noted that only 28 per cent of people in the country have taken booster dose. Corbevax is manufactured by Hyderabad-based Biological E.

Dr Reddy said that the vaccine is easy to manufacture and it is already available in the market at a price of Rs 250.

He suggested that China should also import Corbevax to save lives.

Dr Reddy also made it clear that there is no need for panic as the both the central and state governments are taking necessary measures and adequate stocks of vaccines and Remdesivir are available.

He believes that the number of Covid cases may increase over the next two months but from March next year, the situation will be normal.

He said people should wear masks while going in crowded places. He believes that the impact of the new variant of Omicron will not be severe.

Mumbai Press Exclusive News

On the 33rd anniversary of the Babri Masjid demolition, Mumbai’s streets reverberated with chants of “Allahu Akbar.”Peaceful protests and prayers for recovery were offered, with police on alert.

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On the 33rd anniversary of the Babri Masjid demolition in Mumbai, mosques, streets, and intersections in the city and suburbs echoed with the call to prayer of Allahu Akbar, Allahu Akbar, when the miscreants had demolished the Babri Masjid at 3:45 pm. Muslims believe that the Babri Masjid is a mosque from the throne to the floor and will remain a mosque until the Day of Judgment. Therefore, Muslims observed a black day of protest on December 6. Prayers were also offered for the recovery of the Babri Masjid on this occasion. Raza Academy had announced to observe a black day on the martyrdom of the Babri Masjid and to give collective azans in mosques. On this occasion, Raza Academy organized azan at the intersections of Muslim-majority areas, especially Minaret Masjid and other mosques. On this occasion, the police had made strict security arrangements. Muslim organizations also observed a black day by giving azan and protesting on the martyrdom of the Babri Masjid. Muslims also remembered the grief of the martyrdom of the Babri Masjid by posting statuses related to the Babri Masjid on social media and every Muslim looked sad.

33rd anniversary of the Babri Masjid demolition; Azans were given in the city on the appeal of Raza Academy. On the occasion of the 33rd anniversary of the Babri Masjid demolition, Raza Academy gave azan in different areas of the city at 3:45 pm. The aim of this initiative is to keep the memory of this historical event fresh and pay tribute to the martyrs of Babri Masjid. Raza Academy gave azan in particular at Khatri Masjid, Bunyan Road, Minare Masjid, Muhammad Ali Road Corner, Bhandi Bazaar, Neer Mandvi Post Office. On this occasion, scholars prayed for the recovery of Babri Masjid and made it clear that Babri Masjid was taken by fraud. Babri Masjid will remain a mosque until the Day of Judgment. The miscreants have tarnished the constitution of the country by demolishing this mosque, which will always remain a fresh wound like injustice. Raza Academy head Saeed Noori said that Black Day is observed on the martyrdom of Babri Masjid. On this day, Raza Academy organizes Azan and peaceful protests are held against this injustice. He said that miscreants targeted the mosque and martyred it while it was protected, but even today its perpetrators are free. The Supreme Court has also accepted that Babri Masjid was not built by demolishing a temple, while miscreants have put a stigma of oppression and injustice on the chest of the country. Every year on the anniversary of Babri Masjid, Raza Academy refreshes its memory by giving Azan. There is a sorrow that will always remain. Mumbai Police had made strict security arrangements on the anniversary of Babri Masjid and an alert was issued in the city.

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Maharashtra

Mumbai Additional Municipal Commissioner Amit Saini has been transferred and replaced by IAS officer Avinash Dhakne following allegations of a “cash-for-transfer” scam.

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The transfer comes after an exposé revealed alleged corruption involving the reshuffling of over 160 engineers in the Brihanmumbai Municipal Corporation (BMC), which was subsequently stayed by the government.

A complaint was filed by activist Sanjay Satam to Municipal Commissioner Bhushan Gagrani, alleging that Saini was charging between ₹5 lakh and ₹40 lakh to transfer engineers.

Saini, a 2007-batch IAS officer, had been posted in the BMC since March 2024.
Avinash Dhakne, a 2017-batch IAS officer, previously served as the member secretary of the Maharashtra Pollution Control Board (MPCB) and has taken charge.

The transfers followed demands from activists for action, with Galgali thanking Chief Minister Devendra Fadnavis for the decision.

Activist Satam stated that the transfer is insufficient and called for a departmental and Anti-Corruption Bureau (ACB) investigation into the matter.

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Maharashtra

Maharashtra Waqf Board approached the Tribunal regarding extension of date, don’t worry, 100% registration is assured: Chairman Sameer Qazi

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Aurangabad: (F.A.) The last date for registration on the UMID portal for all registered waqf organisations in Maharashtra, including mosques, dargahs and graveyards, was today, December 5, 2025, which has now expired. Although most of the waqf organisations in Maharashtra have been registered on the portal, some organisations are still missing out due to unavailability of records or other paper errors. In view of this situation, Maharashtra State Waqf Board President Sameer Qazi has appealed to the concerned trustees, trustees and the Muslim community not to panic or believe in any rumours. He has confidently said that: The Waqf Board will complete the registration of every institution. Although the Supreme Court has refused to extend the date, it has allowed the Waqf Tribunal (Waqf Court). The State Waqf Board has approached the tribunal and we are confident that justice will be done there and the deadline for registration on the UMID portal will definitely be extended. Chairman Qazi expressed his firm resolve and further said that the board will not sit in a hurry without the registration of every Waqf institution in the state being completed.

Maharashtra ranks second in the country: 80 percent registration completed.

The registration of all organizations related to the Waqf Board has been completed at a fast pace on the UMID portal. The state of Maharashtra ranks second in the country in terms of registration of Waqf institutions. There are a total of 36 thousand registered Waqf properties in Maharashtra, out of which about 30 thousand (80 percent) properties of organizations have been successfully registered on the UMID portal. All the officers and staff of the Waqf Board have made additional arrangements and completed the registration process. Not only this, but 300 young technicians were hired at the Hajj House in Chhatrapati Sambhaji Nagar to expedite registration on the Omid portal, which is a commendable effort by the board.

Waqf Tribunal issues urgent notice to the central government, seeks response by December 10
Immediately after the Supreme Court’s direction, the Maharashtra Waqf Board approached the Waqf Tribunal. The tribunal has issued a notice to the central government while hearing the matter urgently. The notice asks the centre: “Why should the deadline not be extended?” and has directed it to file its reply by December 10. Due to this urgent action and notice by the tribunal, there is a strong possibility of an extension in the deadline, which has brought a big relief to the waqf institutions.

Don’t pay attention to rumors, time has not been extended.

A statement by Union Minority Affairs Minister Kiren Rijiju was circulating on TV and social media throughout the day today, in which he said that although the trustees have not received any relief, there is hope of getting an extension in time from the tribunal. He also said that no penalty will be imposed on the institutions that approach the tribunal. President Sameer Qazi, while explaining this statement, said: The Minister has not extended the time for uploading on the portal, but has only set a time of three months for checker and approval for those institutions that have already been registered. He explained that false news about the extension in time is being spread on social media, so do not be fooled by any kind of hesitation and until the official extension is done, the institutions must complete the uploading process.

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