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Corbevax booster gives maximum protection, reveals Hyd hospital study

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 Amidst concerns of a new Covid wave in India following massive surge in China and other countries, research at AIG Hospitals here has revealed that Corbevax booster in individuals vaccinated with Covishield gives maximum protection against Omicron variants.

The scientific study has proved the immunity benefits of indigenous heterologous vaccine booster, Corbevax in combating Omicron variants.

The study titled “Heterologous booster dose with Corbevax following primary vaccination with Covishield enhances protection against SARS-CoV-2” has been published in the high-impact factor journal “Vaccines”.

Announcing the findings of the study, AIG Hospitals Chairman Dr D Nageshwar Reddy told media persons that the study was done on 250 healthcare workers who had received 2 doses of Covishield as the primary vaccine regimen not more than 6 months ago. None of the participants had any adverse events following the administration of Corbevax booster dose.

“We knew from our previous studies that mixed vaccines produce better immune response; therefore, when the government approved Corbevax to be given as a heterologous booster to individuals already vaccinated with Covishield, our aim was to determine how a different vaccine platform (protein-based) will impact the immune response especially in context of the Omicron variant,” he said.

Corbevax is an indigenously developed peptide-based vaccine which is different from the viral vector (Covishield) or the inactivated vaccine (Covaxin). The key difference is that Corbevax uses only a protein subunit of the virus replicated inside a yeast cell while the others are whole virus vaccines. The advantage of peptide-based vaccine is that it considerably reduces the risks of allergic and autoimmune responses making them safe for widespread usage.

Dr Reddy said the results further cemented their belief that mixed vaccines are absolutely safe. “The second aspect of the study was to measure the antibody response as well as the T-cell (memory cell) response at 30 days and then at 90 days to correctly estimate the overall protection against the circulating Omicron variant.

When estimating the effectiveness of a vaccine, both the antibody response and T-cell (Memory cell) response are essential.

“In our study, we compared the immune responses among those individuals who were given the same vaccine, i.e., Covishield (homologous group) as a booster and those who were given Corbevax as a booster (heterologous group). The S1/S2-spike protein IgG antibody levels and T/B Cell response of these groups were compared at 30 days and at 90 days. While the homologous and heterologous groups showed increased S1/S2-spike protein IgG antibody level at 30 days, the heterologous group (Corbevax as a booster) showed higher levels of antibodies at both 30 days and 90 days,” Dr Reddy said.

The study was undertaken when Omicron variants are circulating in India; therefore, it would be appropriate to say that heterologous booster (Corbevax) would be effective in combating any wave that is fueled by sub-variants of the Omicron.

High-risk group people should consider taking the booster dose and continue to take Covid appropriate precautions all the time especially when in public spaces.

Replying to queries, Dr Reddy said if a person has taken Covaxin double dose, he should also take Corbevax as the booster dose. “The booster dose should be from the other company as this gives more protection,” he said.

He noted that only 28 per cent of people in the country have taken booster dose. Corbevax is manufactured by Hyderabad-based Biological E.

Dr Reddy said that the vaccine is easy to manufacture and it is already available in the market at a price of Rs 250.

He suggested that China should also import Corbevax to save lives.

Dr Reddy also made it clear that there is no need for panic as the both the central and state governments are taking necessary measures and adequate stocks of vaccines and Remdesivir are available.

He believes that the number of Covid cases may increase over the next two months but from March next year, the situation will be normal.

He said people should wear masks while going in crowded places. He believes that the impact of the new variant of Omicron will not be severe.

Maharashtra

Visit to Deonar Bakra Mandi on the occasion of Eid-ul-Adha, important meeting led by Mumbai Congress President Prof. Varshatai Gaikwad

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Mumbai: On the auspicious occasion of Eid-ul-Azha, a delegation led by Lok Sabha MP and Mumbai Congress President Smt. Prof. Varshatai Gaikwad saheb visited Deonar Bakra Mandi (Slaughterhouse).

On this occasion, she had a special meeting with the General Manager of Deonar Slaughterhouse, Mr. Kaleem Pasha Pathan and discussed in detail the problems faced by the public and traders present in the mandi.

The main points of the discussion were as follows:

Problems faced by traders
Care and maintenance of animals
Cleanliness situation in the mandi
Traffic problems and their solutions
Difficulties faced by common citizens

Professor Gaikwad saheb gave necessary instructions to the concerned authorities for the early resolution of all these problems and assured that Mumbai Congress stands with the people.

Honorable MLA Mr. Aslam Sheikh Sahib, Honorable MLA Mr. Amin Patel Sahib, MLA Dr. Jyoti Tai Gaikwad Sahib, former Corporator and former Chairman of Mumbai Congress Minority Wing Haji Babbu Khan Sahib and other senior leaders and office bearers of Mumbai Congress were also present in this important visit.

The visit was a positive effort for mutual discussions, identification of problems and effective steps to resolve them, which makes an auspicious occasion like Eid more meaningful.

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Maharashtra

ATS crackdown on 22 members including suspected member of Padgha Daesh Saqib Nachan, ATS conducted midnight operation on relatives

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Mumbai: The Maharashtra Anti-Terrorism Squad (ATS) has claimed to have seized several important documents and items during raids at the homes of Saqib Nachan, a former member of ISIS and Students Islamic Movement of India (SIMI), and 22 of his close associates and relatives. The ATS had received information that important documents and other items were hidden at the homes of Saqib Nachan and his close associates, after which the ATS launched the raids at 2 am last night and the operation continued till 4 am, after which the ATS team left for Mumbai. During this operation, the ATS team also cordoned off the entire area. In Borivali Pargham, ATS has conducted raids on Abid Ashraf Mulla, Moaz Mulla, Aqib Saqib Nachan, Abdul Latif Shadab Kaskar, Urmesh Irfan Mulla, Hashim Nadvi, Farooq Mulla, Nabeel Malik Khot, Qais Arif Khot, Kaif Nachan, Sahil Munyar, Adnan Mulla, Shero Deokar, Sharjeel Nachan, Sajid Nachan, Zeeshan Mulla, Atif Mulla, Shams Khot, Asjad Mulla, Raif Khot, Abid Khot. During this time, some of them were on Hajj trips, so they were not present at home.

In this case, ATS conducted raids and did not arrest anyone during house searches. Zubair Mulla, a resident of a small mosque who deals in land, was on a Hajj trip. Zubair Mulla was convicted in the 2002 and 2003 bomb blasts and was also sentenced. Now he is lodged in Delhi jail along with Saqib Nachan in the case of ISIS connection in Delhi. Abdul Latif Kaskar is employed in Godam and is also a friend of Farhan Sousa in the Delhi ISIS case. Shams Khot, Rais Khot, Abid Ashraf Mulla, Moaz Ashraf Mulla, Qais Asif Khot were not present at the house during the search, while a raid was conducted at Kalyan’s house in Sahil Munyar and he was also not present here.

ATS had found Saqib Nachan active in terrorist activities again since 2017. During this time, ATS had kept an eye on him and a case was also registered against him, but in this case, NIA had arrested Saqib Nachan in the ISIS case. First, his son Aqib Nachan was arrested and then Saqib will also be arrested. ATS has also claimed to have seized several important documents during the operation, which will be investigated and then the action will progress accordingly. Maharashtra ATS has conducted raids at 15 places including Mumbai police station Bhiwandi Kalyan and during this, action has also been taken against suspected members of ISIS. In this operation, ATS is expected to find many important documents and evidence. The ATS has taken action in this case against those accused of being involved in anti-national and illegal activities. ATS is taking further action in this case, while no arrest has been made so far after searching anyone.

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Maharashtra

Mumbai Ghatkopar dispute over Qurbani, police security increased, situation tense after objections to Qurbani, police monitoring

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Mumbai: A controversy has arisen over the Qurbani in Damodar Society in Mumbai’s Ghatkopar area. So far, the BMC has not granted permission for a temporary slaughterhouse in the society. Society member Bharatiya has alleged that before the sacrifice, goats are brought into the society and spread dirt and an atmosphere of fear is created here during the sacrifice because Hindus are migrating from this society while the sacrifice process has been going on in the society for the past twenty-five years. Society member Ishtiaq said that all festivals are celebrated in the society but only two women have objection and they are spoiling the atmosphere here because they have a personal issue with the society and therefore this issue is being given a Hindu-Muslim color.

He said that for the sacrifice, a canopy is prepared in the ground and the sacrifice is performed and cleanliness is also taken care of. Along with this, the meat is taken covered. He said that after the announcement of the mischief of Kirit Somaiya and the announcement of not allowing the sacrifice in the society, these two women have also complained here while the BMC society has contacted and if the society does not get permission, it will approach the court because the court has allowed the sacrifice before too. Muslims say that these two women are spoiling the atmosphere here due to the sacrifice issue. While there is peace and order and Hindu-Muslim unity here, only these two women have objections to the sacrifice. We will also knock on the door of the court to perform the sacrifice legally. After this controversy, the Vikhroli Park Site Police have tightened security arrangements.

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